Over 35 Years of Providing Cancer Treatment and Research

At the START Center, we provide leading-edge cancer treatment backed by a deep commitment to advancing toward a new era in cancer care. Our team strives to offer each patient a comprehensive treatment plan that includes multi-specialty services, genetic profiling of tumors, targeted therapies, state-of-the-art treatment technology, and easy access to clinical research options.

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Why Choose START


At The START Center, our mission is to provide leading-edge, compassionate cancer treatment backed by a deep commitment to advancing towards a new era in....

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Our Providers


At the START Center, our surgeons, medical oncologists, radiation oncologists, and gynecologic surgical oncologists have the combined knowledge, skill...

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Our History


South Texas Oncology and Hematology was founded in 1985 by Dr. Lon Smith and Dr. Steven Kalter. Their mission was to provide high-quality research, treatment...

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Over 35 Years of Providing Cancer Treatment

At the START Center, we provide leading-edge cancer treatment backed by a deep commitment to advancing toward a new era in cancer care. Our team strives to offer each patient a comprehensive treatment plan that includes multi-specialty services, genetic profiling of tumors, targeted therapies, state-of-the-art treatment technology, and easy access to clinical research options.

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Why Participate in a Clinical Trial?
With your participation in a clinical trial, we can develop new cancer treatments that will change how the world fights cancer. The cure STARTs here.
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At START, we conduct clinical research to discover novel anti-cancer agents. With over 28 approved oncology drugs, START is a leader in global cancer research.

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Our offices provide a variety of advanced cancer treatment services with continually advancing sophistication and effectiveness.

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START has various locations across the United States and Europe. We are ready to help treat you or a loved one's cancer with the compassion they deserve.

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Your START Care Team

The doctors in our practice have some of the most advanced oncology expertise in the world. They are here to guide you through your cancer treatment and provide you with exceptional care. We often hear from patients that being treated by a START physician is a personal and compassionate experience.

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